According to the Ministry of Health survey, China now there are at least 34 million diabetics, accounting for 2.6% of the total population.
In the 30 years ago, the figure was only 0.7%. According to the World Health Organization predicts that by 2025 the world will have 300 million diabetes patients, while China is likely to become diabetic, "superpower."
Experts have long suggested that diabetes is a "source of sickness" in a variety of chronic diseases, diabetes is the most painful for patients. In order to sustain life, the patient can not do without daily insulin and drugs; because the body lacks insulin or the body does not use insulin, patients are often hesitant to eat, casual move, always worried about blood sugar, life-threatening; In addition, Diabetes also affects blood vessels and nervous system, causing high blood pressure, stroke and other diseases --- can be said, have diabetes, human life becomes fragile.
Great harm because of diabetes, the incidence of more serious, therefore, overcome diabetes and make diabetes more relaxed life, has been the focus of the international medical community. Conquering diabetes in the end how long? With this issue, the domestic newspaper reporters in the field of diabetes research and treatment of several experts, the same time, newspaper reporters in the Danish research in diabetes is a global leader Dan Mainuo Nordisk to contact, interview the vice president and chief scientific officer Maizi hole Sigma Dr. Tang Musen.
Drug: control blood sugar more "intelligent"
At Copenhagen, Denmark Novo Nordisk headquarters, reporters saw Dr. Tang Musen. He is a quick thinking, and often people can not keep up the rhythm of diabetes experts. Interview, he told reporters on the road in the conquest of diabetes, scientists have made the latest developments.
Dr. Tang Musen told reporters that one of the biggest troubles with diabetes not on insulin to move on from dependency, so scientists have been studying how to reduce diabetic medication visits and also increase the drug's safety. He said that recently, one called glucagon-like peptide -1 of the natural hormone has been of great concern to the medical profession, the use of this material, we can develop a more secure, convenient diabetic drugs. He told reporters that there is a body called glucagon substances will stimulate glycogenolysis to glucose levels. In eating, gut will release glucagon-like peptide -1. On the one hand on the role of the brain to reduce appetite; the one hand, stimulates the body to secrete insulin, suppress glucagon, lower blood sugar.
Dr. Tang Musen that processed glucagon-like peptide -1 24 hours to take effect in the human body as long as the blood glucose level higher than normal, it can be mobilized, "suppress" blood sugar. Moreover, and insulin than taking glucagon-like peptide -1 drugs can blood sugar down to normal levels, then medication will no longer have an effect; the insulin dose must be carefully controlled, because excessive nitrogen will lead to low blood sugar, severe life-threatening. Obesity is the cause of type 2 diabetes is an important factor, glucagon-like peptide -1 can suppress appetite, but also conducive to weight loss. Dr. Thomson, if goes well, glucagon-like peptide -1 drug
Materials will be available this winter for the third phase of clinical trials. In addition, the reporter also learned that some new drugs will focus placed to help patients get rid of the pain of the needle injection. Indian experts have developed an oral medication, to encapsulate insulin, has been released into the intestine before. In addition, scientists also developed a package of insulin, patients can "absorb" the way of insulin. It is reported that the drug will be listed this year.
Surgery: cell transplantation for patients with insulin-free
In addition to actively developing new drugs, through surgery and other aspects of diabetes, scientists have also made no small achievement. British Broadcasting Corporation (BBC) report, from last September to the end of January this year, Britain has a 61-year-old Mingjiaolaien type 1 diabetes patients received 3 islet β cell transplant. Now, in addition to regularly take anti-rejection drugs he has no need to inject insulin up. He said: "I feel like a changed man." King's College London medical experts believe that, for type 1 diabetes, this is an exciting news. It is reported that Japan, Canada and other countries have carried out such transplant. Among them, Japan's first female patient transplanted islet β cells in the mother, 22 days after surgery to get rid of the insulin.
Dr. Tang Musen also noted that Novo Nordisk is studying the artificial pancreas. Artificial pancreas is mounted on the body's micro-devices, real-time detection of blood glucose levels, then the release of insulin based on test results, the patients, a convenient and timely. Dr. Tang Musen optimistic that these results will significantly improve the lives of diabetics. The reporters also learned that scientists at the University of California, is also studying artificial pancreas.
Early diagnosis: The new method improves the detection rate
Treatment of diabetes continues to improve at the same time, the early detection of diabetes have also been seen. Cadres from Beijing Tongren Hospital's Medical Section, where the attending physician Zhou Jian understand that about 80% of diabetes patients is found in the examination, to identify the problem, many people have been very ill. He believes that this figure adequately illustrates the importance of early diagnosis. Shanghai Diabetes Institute, Professor Jia Weiping told reporters: "There is about 50% of diabetes patients appears quite normal, loud, red, move easily, if not to the hospital for tests, it may not even know that they got sick, naturally not take treatment measures. "
The current comprehensive study mainly diabetes screening fasting plasma glucose and postprandial glucose, and then make a diagnosis. Duke University researchers have invented a name HgA1c early diagnosis of type 2 diabetes means the body by detecting the six weeks the average blood glucose level to screen for diabetes, to improve the detection accuracy. Their 1235 high risk groups of subjects were examined and found that 4.5% of people with diabetes, the final detection rate of 75%, while using traditional screening methods, many patients have shown "no disease."
In addition to HgA1c detection, scientific director of the South African Medical Research Council has also invented a type 2 diabetes detection: determination of blood insulin and insulin ratio before. Before the insulin is a protein secreted by the pancreas, transformed into insulin, but patients with type 2 diabetes before insulin but does not become insulin. Therefore, by detecting the ratio of two substances, you can find diabetes.
Also 23 years to conquer diabetes
With so many drugs, surgical and diagnostic methods, then, to conquer diabetes, the most fundamental way is what? Dr. Tang Musen that the cure for this disease hope in stem cells. "Stem cells can grow into any cell." He told reporters, stem cells can produce insulin into pancreatic β cells should only be a matter of time, and now the key is to find ways transform. He pointed out that to complete the stem cells into pancreatic β cells, is about 20 years, they need to conduct clinical trials for 10 years, that is, to cure diabetes, and have to wait 23 years. He told reporters that for now, type 2 diabetes is most likely to be the first radical. From the China expert on diabetes, diabetes credits the Chinese Medical Association, chairman of items where the learned academician Kunsan, China's diabetes patients, 85% of people suffer from type 2 diabetes. Therefore, Thomson predicted Dr. diabetes in China is undoubtedly a good news.
In addition to stem cells, gene therapy is currently the focus of global concern. Item academician told reporters that China had approximately 5% of people with diabetes have the special type. This diabetes is a gene of a human body, "bad" caused by single gene mutations, also known as diabetes. Now, international studies have it as a breakthrough to a single gene through the problems caused by diabetes, and multiple genes causing type 2 diabetes also have conquered the hope.
In addition, the reporter also learned that foreign scientists are studying diabetes vaccine. Recently, King's College London University of Bristol, prepared jointly with the world's first human trials of type 1 diabetes vaccine. This vaccine into human blood, the effect of protecting cells, blocking the white blood cells destroy β cells. If successful, will diabetes research a major step forward.
Chinese people prone to diabetes than Westerners
Although diabetes is a worldwide topic, but Dr. Tang Musen that Chinese people pay particular attention to prevention and treatment of diabetes. He said that as East and West of the gene, the Chinese are more likely to develop diabetes. 30% of Americans are fat and body weight only when the risk of diabetes, while China may have 23% of body weight is fat, he had already suffering from type 2 diabetes was. In addition, he also told reporters that China's rural areas, 2% -3% of people suffering from diabetes, the prevalence of Beijing and other places even close to 10%, and most patients did not receive good treatment. 2030, China may increase the number of people with diabetes doubled to 70 million. Professor Jia Weiping pointed out that from the perspective of China's population distribution, family history of diabetes, more fat (especially belly big, thin legs), 45 over the age of high risk groups. Mental and work pressure, entertainment and more people have a relatively high incidence.
Dr. Tang Musen told reporters, according to surveys, 58% of the world of diabetes and obesity, in some countries, this ratio is as high as 90%. Now, many Chinese people who blindly follow the Western way of life: eating high-calorie food, car travel, the result more and more obese, the rising incidence of diabetes. He was with concern that in accepting the training of people to prevent diabetes, only 1/4-1/3 people living in accordance with guidance to improve, therefore, have to carry on educational work. Professor Jia Weiping said, as long as diabetes and to take effective treatment, adhere to a healthy lifestyle, not only able to live a happy life, but also longevity.
Saturday, May 1, 2010
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